SEM6D Rabbit Polyclonal Antibody

Description: A polyclonal antibody for detection of SEM6D from Human, Mouse. This SEM6D antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human SEM6D protein

Description: Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.

Description: Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.

Description: Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.

Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Description: Available in various conjugation types.

Description: SEM6D Rabbit Polyclonal Antibody

Description: SEM6D Rabbit Polyclonal Antibody

Description: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins| semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities| semaphorins are put into eight classes: invertebrates contain classes 1 and 2| viruses have class V| and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes| some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Description: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins| semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities| semaphorins are put into eight classes: invertebrates contain classes 1 and 2| viruses have class V| and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes| some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Description: Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins| semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities| semaphorins are put into eight classes: invertebrates contain classes 1 and 2| viruses have class V| and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes| some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Description: The transcription of this gene is activated by PPAR-gamma| and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion.

Description: The transcription of this gene is activated by PPAR-gamma| and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion.

Description: The transcription of this gene is activated by PPAR-gamma| and the resulting protein product plays a role in endothelial cell migration. Expression of this gene also inhibits tumor cell migration and invasion.

Description: This gene encodes a transmembrane class IV semaphorin family protein| which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer| the development of neurofibromas| and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.

Description: This gene encodes a transmembrane class IV semaphorin family protein| which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer| the development of neurofibromas| and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.

Description: This gene encodes a transmembrane class IV semaphorin family protein| which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer| the development of neurofibromas| and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants.

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: WB, ELISA

Description: The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides| SgI-29| is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20.

Description: The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides| SgI-29| is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20.

Description: The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides| SgI-29| is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20.