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Response of breast cancer carcinoma spheroids to combination therapy with radiation

Posted on by Frank
Response of breast cancer carcinoma spheroids to combination therapy with radiation and DNA-PK inhibitor: Growth arrest with no change in α/β ratio   Agents that enhance tumor radiosensitivity are of curiosity in enhancing outcomes in radiotherapy (XRT). DNA-PK inhibitors lead to radiosensitization and in addition to alterations in cell adhesion proteins. We investigated the combination of radiation and a DNA-PK inhibitor in monolayer vs...

Vitamin D and its Effects on DNA Methylation in Development, Aging and Disease

Posted on by Frank
Vitamin D and its Effects on DNA Methylation in Development, Aging and Disease  DNA methylation is more and more being recognised as a mechanism by means of which environmental exposures confer illness threat. Several research have examined the affiliation between vitamin D and modifications in DNA methylation in areas as various as human and animal improvement, genomic stability, power illness threat and malignancy. In many circumstances,...