Malignant transformation in a Breast Adenomyoepithelioma Caused by Amplification of c-MYC: A Common pathway to Cancer in a Rare Entity.
Breast adenomyoepitheliomas are composed of a biphasic proliferation of myoepithelial cells round small epithelial-lined areas. Due to the rarity of adenomyoepitheliomas, the molecular knowledge describing them are restricted. Adenomyoepitheliomas are thought-about to be benign or have low malignant potential, and be susceptible to native recurrence. Malignant transformation has been related to homozygous deletion of CDKN2A or somatic...