PITX1 protein interacts with ZCCHC10 to regulate hTERT mRNA transcription.
Telomerase is a ribonucleoprotein ribonucleic enzyme that's important for mobile immortalization by way of elongation of telomere repeat sequences on the finish of chromosomes. Human telomerase reverse transcriptase (hTERT), the catalytic subunit of telomerase holoenzyme, is a key regulator of telomerase exercise. Telomerase exercise, which has been detected within the majority of most cancers cells, is accompanied by hTERT expression,...